8-Hydroxyquinoline (8-HQ)
Khoom Muag: 8-Hydroxyquinoline (8-HQ) nrog rau qhov zoo
CAS#:148-24-3
Cov mis molecular: C9H7NO
Cov Qauv Qauv:
Siv: Tshuaj intermediates; Tshuaj tua kab thiab xim intermediates
Cov Lus Qhia:
| Khoom | Tus Qauv |
| Qhov tsos | Yuav luag dawb los yog xim av daj crystalline hmoov los yog spiculate crystals |
| Tsw tsw phem | Phenolic |
| Tshuaj (10% hauv alc) | Yuav luag meej meej |
| Cov hlau hnyav | ≤20ppm |
| Cov seem ntawm kev hlawv | ≤0.2% |
| Hlau | ≤20ppm |
| Ntau yam yaj | 72-75 ℃ |
| Chloride | ≤0.004% |
| Sulfate | ≤0.02% |
| Kev Ntsuas | 99-99.8% |
| 5-Hydroxyquinoline | ≤0.2% |
Kev Txiav Txim Siab
Yaj hauv ethanol, acetone, chloroform, benzene thiab mineral acid, yuav luag insoluble hauv dej.
8-hydroxyquinoline yog amphoteric, soluble nyob rau hauv cov kua qaub thiab cov hauv paus muaj zog, ionized rau hauv cov ions tsis zoo hauv cov hauv paus, khi rau hydrogen ions hauv cov kua qaub, thiab muaj qhov solubility qis tshaj plaws ntawm pH = 7.
Kev siv tshwj xeeb
1. Ua ib qho tshuaj nruab nrab, nws tsis yog tsuas yog cov khoom siv raw rau kev tsim cov kexieling, chloroiodoquinoline thiab paracetamol, tab sis kuj yog qhov nruab nrab ntawm cov xim thiab tshuaj tua kab. Cov khoom no yog ib qho nruab nrab ntawm cov tshuaj halogenated quinoline anti amoeba, suav nrog quiniodoform, chloroiodoquinoline, diioquinoline, thiab lwm yam. Cov tshuaj no ua lub luag haujlwm tiv thaiv amoeba los ntawm kev tiv thaiv cov kab mob hauv plab hnyuv. Lawv zoo rau amoeba dysentery thiab tsis muaj kev cuam tshuam rau extraintestinal amoeba protozoa. Nws tau tshaj tawm txawv teb chaws tias hom tshuaj no tuaj yeem ua rau subacute spinal cord optic neuropathy, yog li nws tau raug txwv hauv Nyiv thiab Tebchaws Meskas. Diioquinoline ua rau tus kab mob no tsawg dua li chloroiodoquinoline. 8-hydroxyquinoline kuj yog ib qho nruab nrab ntawm cov xim thiab tshuaj tua kab. Nws cov sulfate thiab tooj liab ntsev yog cov tshuaj preservatives zoo heev, tshuaj tua kab mob thiab cov neeg sawv cev tiv thaiv mildew. Cov khoom yog ib qho qhia complexometric rau kev tshuaj xyuas tshuaj.
2. Ua ib tug neeg sawv cev thiab extractant rau nag lossis daus thiab kev sib cais ntawm cov hlau ions, nws tuaj yeem cuam tshuam nrog Cu+ 2, ua+ 2, Mg+ 2, Ca+ 2, Xib Hwb+ 2, Ba + 2 thiab Zn+ 2,Cd+2,Al+3,Ga+3,In+3,Tl+3,Yt+3,La +3,Pb+2,B+3,Sb+ 3,Cr+3,MoO+ 22Kev sib xyaw ua ke ntawm Mn+ 2,Fe+ 3, CO+ 2, Ni+ 2, PD+ 2, CE+ 3, thiab lwm yam hlau ions. Organic microanalysis, tus qauv rau kev txiav txim siab ntawm heterocyclic nitrogen, organic synthesis. Nws kuj yog ib qho nruab nrab ntawm cov xim, tshuaj tua kab thiab halogenated quinolines. Nws cov sulfate thiab tooj liab ntsev yog cov tshuaj preservatives zoo heev.
3. Ntxiv cov nplaum epoxy resin tuaj yeem txhim kho lub zog sib txuas thiab tiv taus kev laus ntawm cov hlau (tshwj xeeb tshaj yog cov hlau tsis xeb), thiab feem ntau cov koob tshuaj yog 0.5 ~ 3 phr. Nws yog ib qho nruab nrab ntawm cov tshuaj halogenated quinoline anti amoeba, nrog rau ib qho nruab nrab ntawm cov tshuaj tua kab thiab cov xim. Nws tuaj yeem siv ua cov tshuaj tiv thaiv kab mob mildew, cov tshuaj tiv thaiv kev lag luam, cov tshuaj stabilizer ntawm polyester resin, phenolic resin thiab hydrogen peroxide, thiab tseem yog cov cim qhia titration complexometric rau kev tshuaj xyuas tshuaj lom neeg.
4. Cov khoom no tsis yog tsuas yog cov khoom nruab nrab ntawm cov tshuaj halogenated quinoline xwb, tab sis kuj yog cov khoom nruab nrab ntawm cov xim thiab cov tshuaj tua kab. Nws cov sulfate thiab ntsev tooj liab yog cov tshuaj preservatives, tshuaj tua kab mob thiab cov neeg sawv cev tiv thaiv pwm zoo heev. Cov ntsiab lus siab tshaj plaws (feem pua ntawm qhov hnyav) hauv cov tshuaj pleev ib ce yog 0.3%. Cov khoom siv tshuaj pleev thaiv hnub thiab cov khoom rau cov menyuam yaus hnub nyoog qis dua 3 xyoos (xws li hmoov talcum) raug txwv, thiab "txwv tsis pub rau cov menyuam yaus hnub nyoog qis dua 3 xyoos" yuav tsum tau qhia rau ntawm daim ntawv lo ntawm cov khoom. Thaum cuam tshuam nrog cov kab mob kis kab mob ntawm daim tawv nqaij thiab cov kab mob eczema, feem pua ntawm 8- hydroxyquinoline hauv cov emulsion yog 0.001% txog 0.02%. Nws kuj tseem siv ua tshuaj tua kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob, thiab nws cov nyhuv tiv thaiv pwm muaj zog. 8- hydroxyquinoline potassium sulfate yog siv rau hauv cov tshuaj pleev ib ce thiab tshuaj pleev ib ce (feem pua ntawm qhov hnyav) ntawm 0.05% txog 0.5%.